A Retrospective Analysis on the Pharmacological Management of Irritable Bowel Syndrome

    Published on:July 2021
    Journal of Young Pharmacists, 2021; 13(2):186-188
    Short Communication | doi:10.5530/jyp.2021.13.38

    Subair MA1, Sharad Chand1, Nandakumar UP1, Ganaraj Kulamarva2, Juno J Joel1,*

    1Department of Pharmacy Practice, Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Deralakatte, Mangaluru, Karnataka, INDIA.

    2Department of Gastroenterology, Justice KS Hegde Charitable Hospital, Nitte (Deemed to be University), Mangaluru, Karnataka, INDIA.


    Objectives: To analyze the pattern of drugs prescribed to treat irritable bowel syndrome among patients admitted in a tertiary care teaching hospital. Materials and Methods: A retrospective study was carried out among 120 inpatients of the general medicine department for a period of eight months from August 2019 to April 2020. The data of the patients admitted to the hospital over a period of five years was collected from the medical records department in a specially designed data collection form. The prescription pattern of the drugs used in the management of irritable bowel syndrome was analyzed using descriptive statistics. Results: Among 120 patients, n=68 were diagnosed with inflammatory bowel syndrome (IBS)-D, n=30 with IBS-M and n=22 diagnosed with IBS-C. The occurrence of irritable bowel syndrome was higher in males (55%) than in females (45%). The most common clinical presentation was found to be abdominal pain, reported among 63.33% of the total patients. Probiotics were the most widely prescribed medications n=73(14.39%), followed by pantoprazole n=65(12.82%). Conclusion: In the study, movement modulators followed by adjunctive gastrointestinal agents, psychoactive substances and antibiotics were commonly prescribed for the management of irritable bowel syndrome.

    Key words: IBS, Pharmacotherapy, Abdominal pain, Colonoscopy, Probiotics.

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