Home J Young Pharm, Vol 8/Issue 2/2016 Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study

Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study

by [email protected]
Published on:Jan/2016
Journal of Young Pharmacists, 2016; 8(2):108-113
Original Article | doi:10.5530/jyp.2016.2.9
Authors:
Ramanath Katta Venkatesh1,2, Mukhyaprana M Prabhu3, Krishnadas Nandakumar1, K Sreedhara R Pai1*

1Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, INDIA.

2Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, BG Nagar, Nagamangala, Mandya District, Karnataka, INDIA.

3Department of Medicine, Kasturba Medical College, Manipal University Manipal-576104, Karnataka, INDIA.

Abstract:

Introduction: Urinary tract infections (UTIs) are more common in geriatrics due to physiological alterations/pathological conditions. The main objective of this study was to analyze the incidence, causative organisms, types of antibiotics used, drug interactions, the antibiotic cost, and its outcome. Method: This is across-sectional study conducted in selected medicine units over a period of 18 months. The enrolled patient’s therapy pattern spotted from the admission to discharge. The mandatory patients provided with pharmaceutical care services. Results and Discussion: Among 475 observed cases, 106 patients had UTIs (22.31%). The mean number of drug were 7.42 ± 2.31per prescription. Out of 106 prescriptions, 63 prescriptions had drug interactions. The drug interactions degree varied from mild (12.63%), moderate (60.3%) and severe (26.58%) remained managed by spacing intervals, alternate drug use, and close monitoring techniques. Strangely, all comorbid UTI patient outcomes showed improvement. The antibiotic cost of the management ranged from $ 0.21-160.8 with a median of $ 26.30 and the common organisms were E. coli (48%), Enterococcus (16%). The average length of patient hospital stay was 11.65 ± 8.94 days. Conclusion: This study showed that about one-fourth patients have UTIs and half of them were affected by E. coli. Hence, this study proposes the paucity and its implication of pharmaceutical care service research studies, on health-hygiene, proper use of antibiotics & its cost minimization; untoward interactions cost prevention, for better outcome in India.

Key words: Urinary tract infection (UTI), Drug interaction (DI), Geriatrics, Hypertension( HTN), Discharge against medical advice (DAMA), Tricyclic antidepressants (TCA), HCT: Hydrocholrothiazide.