Ivabradine: Novel If Channel Inhibitor
1★, 2★ Corresponding author
- 1Faculty of Medicine, AIMST University, MALAYSIA.
- 2Unit of Pharmacology, Faculty of Medicine, MALAYSIA.
Volume 1, Issue 3 · pp. 284 · 2009 · DOI: 10.4103/0975-1483.57073
ABSTRACT
Pacemaker activity of the heart involves interplay between several ionic currents that inß uence spontaneous diastolic depolarization of the sinoatrial node, including If current. The search for pure heart rate-lowering agents to prevent angina without over all adverse effects of β-blockers[1] began more than three decades ago. The discovery of If current and If channels offered a possible approach to the developing pure heart rate-lowering agents.[1]
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H, A., & A, K. (2009). Ivabradine: Novel If Channel Inhibitor. Journal of Young Pharmacists, 1(3), 284. https://doi.org/10.4103/0975-1483.57073
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