Volume 18, Issue 2

Vishwa Rajakumar Byakod, Madiwalayya Shivakantayya Ganachari

pp. 569-577 · DOI: 10.5530/jyp.20260041 · 2026

Introduction: Quality of Life (QoL) reflects an individual’s perception of physical, psychological, social, and environmental well-being and is an important indicator of overall health and life satisfaction. Purpose: Thi…

Afaf Salim Alwabli

pp. 578-586 · DOI: 10.5530/jyp.20260055 · 2026

Background: The NS5 Methyltransferase (MTase) domain of Dengue Virus Serotype 4 (DENV-4) plays a central role in viral RNA capping, genome replication, and immune evasion. Understanding its structural and functional prop…

Shruti Khandke, Vaishanvi Vanshakrithmath, K V Abhishek, V Surendra, Sanatkumar Bharamu Nyamagoud

pp. 587-594 · DOI: 10.5530/jyp.20260076 · 2026

Background: Cardiovascular Diseases (CVD) a leading cause of morbidity and mortality globally. This study aimed to assess the demographic profile, major diagnoses, and Health-Related Quality of Life (HRQOL) in CVD patien…

Nivetha Jasmine Edwardraj, Hemalatha Kuppan, Santhiya Gopalsamy, Manimegalai Karnan

pp. 595-604 · DOI: 10.5530/jyp.20260044 · 2026

Background: The growing incidence of antimicrobial resistance demands the development of new therapeutic agents with improved safety and efficacy. Benzimidazole derivatives are considered promising pharmacophores due to …

Mandava Mahima Swaroopa, Meghana Regulapati, Reshma Gayathri Kassetti, Mohammad Karishma, Kurra Varun

pp. 605-610 · DOI: 10.5530/jyp.20260288 · 2026

Ileocolic intussusception is one of the most common causes of intestinal obstruction in infancy and represents a paediatric surgical emergency. Early diagnosis is essential to prevent bowel ischemia, necrosis, and perfor…