Article · Volume 8, Issue 1 · pp. 12-17

Co-administration effects of α-lipoic acid and nucleo CMP on arousal and sensory cortical activity

Hayder M. Al-kuraishy¹, Ali I. Al-Gareeb¹

¹Department of Pharmacology, Toxicology and Medicine College of Medicine Almustansiriya University, Baghdad, IRAQ.

Abstract

Objective: To evaluate the combined effects of lipoic acid and nuclear CMP on arousal and sensory cortical activity in normal healthy volunteers.Method: Eighty healthy volunteers enrolled in this study, the volunteers were divided into four groups’. Group A: take a placebo and regarded as controlling. Group B: take nucleo CMP capsule 5mg/day. Group C: take lipoic acid 400mg/day. Group D: take nucleo CMP and lipoic acid/ day. The duration of treatment was two weeks. CFFF tests measured via Leeds psychomotor battery tester. Student t-test, simple correlation and ANOVA test via SPSS version 18, taking p0.05. Combined lipoic acid and Nucleo CMP produced significant effects on critical flicker frequency, critical fusion frequency, flicker percent and fusion percent p0.05.Conclusion: lipoic acid and nucleo CMP produced significant arousal effects on normal healthy volunteers and improve cognitive functions.

Keywords: CFFF; Lipoic acid; Nucleo CMP; Sensory cortical activity

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