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Inverted U shaped effect of nicotine on the severity of depressive symptoms: A population-based survey

1★★ Corresponding author

  1. 1Department of Pharmacology, College of Medicine, University of Al-Mustansiriyah, Baghdad 14132, IRAQ.

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Ammar W. Ashor

Department of Pharmacology, College of Medicine, University of Al-Mustansiriyah, Baghdad 14132, IRAQ.

ammar_w_78@yahoo.com

Received: 31-03-2013; Revised: 15-06-2013; Accepted: 08-07-2013.

Volume 5, Issue 2 · pp. 60-63 · 2013 · DOI: 10.1016/j.jyp.2013.06.004

ABSTRACT

Objectives: To investigate whether that nicotine concentration represented by the degree of smoking dependence variably influence the rate and severity of depressive symptoms.Methods: Cross-sectional, analytical study, involving 300 medical students selected by random sampling techniques were asked to complete a questionnaire contains three parts: demographic information, Beck Depression Inventory with cutoff point for depression is 17 and the Fagerström Test for Nicotine dependence with cutoff point for severe dependence is five.Results: A total of 233 medical students completed the questionnaire; their mean age was (21.38 (+-) 1.74). The rate of smoking was 22.7% while that of depressionwas 32.2%. Low dependent smokers in contrast to other groups of smokers and non-smokers display the lowest rate of depressive symptoms (15%), while the highest rate recorded among severely dependent smokers (71.4%, p ¼ 0.0001). After adjustment of other risk factors, regression analysis reveal that severe dependent smokers associated with 12.5 odds of depressive symptoms than non-smokers (p ¼ 0.0001, C.I. 4.10e38.29).Conclusion: In comparison with light and moderate smokers, heavy smokers demonstrate higher risk of depressive symptoms in medical students.

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    Ashor, A. W. (2013). Inverted U shaped effect of nicotine on the severity of depressive symptoms: A population-based survey. Journal of Young Pharmacists, 5(2), 60-63. https://doi.org/10.1016/j.jyp.2013.06.004

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    © 2013 Author(s)

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