Drug Interaction and Pharmacist

    Published on:
    journal of young pharmaceutics, 2010; 2(3):326-331
    General Pharmacy | doi:10.4103/0975-1483.66807

    Ansari JA

    Department of Pharmacology, Faculty of Pharmacy, Hamdard University, New Delhi 110 062, India


    The topic of drug–drug interactions has received a great deal of recent attention from the regulatory, scientific, and health care communities worldwide. Nonsteroidal anti-inflammatory drugs, antibiotics and, in particular, rifampin are common precipitant drugs prescribed in primary care practice. Drugs with a narrow therapeutic range or low therapeutic index are more likely to be the objects for serious drug interactions. Object drugs in common use include warfarin, fluoroquinolones, antiepileptic drugs, oral contraceptives, cisapride, and 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitors. The pharmacist, along with the prescriber has a duty to ensure that patients are aware of the risk of side effects and a suitable course of action should they occur. With their detailed knowledge of medicine, pharmacists have the ability to relate unexpected symptoms experienced by patients to possible adverse effects of their drug therapy.

    Key words: Computerized screening systems, current indian scenario of drug interactions, drug interaction management, drug interactions.