Journal of Young Pharmacists logo
Submit
Journal of Young PharmacistsACADEMIC PUBLISHING
Review

The Effect of Glucosamine With or Without Chondroitin Sulphate on Glucose Monitoring Parameters in Humans – A Systematic Review

1,2★, 2, 2, 1, 1, 1★ Corresponding author

  1. 1Centre of Excellence in Pharmaceutical Sciences, School of Pharmacy, KPJ Healthcare University College, Nilai, MALAYSIA.
  2. 2Faculty of Pharmacy, University of Cyber Jaya, Cyber Jaya, Selangor, MALAYSIA.

CORRESPONDENCE

Bama VV Menon

Centre of Excellence in Pharmaceutical Sciences, School of Pharmacy, KPJ Healthcare University College, Nilai, MALAYSIA.

bamamenon@kpjuc.edu.my

Received: 24-11-2020; Revised: 16-12-2020; Accepted: 09-01-2021.

Volume 13, Issue 1 · pp. 19-24 · 2021 · DOI: 10.5530/jyp.2021.13.4

ABSTRACT

Musculoskeletal diseases that included OA was the second greatest contributor to disability as measured by years lived with disability. The goals of OA treatment are to reduce pain, improve function and quality of life and decrease disability. The objective of this systematic review is to summarise the findings of the effect of glucosamine with or without chondroitin sulphate on glucose monitoring parameters in humans. An English language literature search of electronic bibliographic databases such as Medline, Web of Science, Science Direct, Scopus and Cochrane since inception to June 2020 was conducted. Two reviewers independently analysed the studies for quality and content using the Downs and Black Checklist. The thirteen studies that were included in the review consists of randomised control trials (n=7), non-randomised control trials (n=3), prospective cohort studies (n=2) and pre-post studies (n=1). Five studies detected the effect of glucosamine on glucose parameters. Studies that recruited patients with baseline impaired glucose tolerance or insulin resistance were more likely to detect an effect on glucose metabolism. Patients taking glucosamine have a higher risk of diabetes especially those who have high baseline glucose levels or have diabetes or have impaired glucose tolerance. Only two studies investigated the effect of glucosamine on glucose parameters in patients having osteoarthritis.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Menon, B. V., Hashim, R., Zainal, Z. A., Kalusalingam, A., Khan, A., & Siang, T. C. (2021). The Effect of Glucosamine With or Without Chondroitin Sulphate on Glucose Monitoring Parameters in Humans – A Systematic Review. Journal of Young Pharmacists, 13(1), 19-24. https://doi.org/10.5530/jyp.2021.13.4

    Copyright and licence

    © 2021 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0