Parenteral Cyanocobalamin Induced Arthralgia: A Case Report
1★, 2, 3★ Corresponding author
- 1Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, TANZANIA.
- 2Department of Pharmacology, MGM New Bombay Hospital, Vashi, Navi Mumbai, Maharashtra, INDIA.
- 3Department of Pharmacy Practice, JSS College of Pharmacy, Ootacamund, Ooty, Tamil Nadu, INDIA.
CORRESPONDENCE
Kabakama Clement Jr
Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, TANZANIA.
Received: 29-05-2020; Revised: 16-07-2020; Accepted: 05-10-2020.
Volume 12, Issue 4 · pp. 383-385 · 2020 · DOI: 10.5530/jyp.2020.12.97
ABSTRACT
Cyanocobalamin is a presently coenzyme mainly involved in reactions leading to synthesis of Nucleic Acids and of that of methionine from homocysteine. On the other hand hematological neurological and epithelial clinical manifestations observed during Vitamin B12 deficiency may lead to Pernicious anemia. Pernicious anemia is a megaloblastic anemia which leads to abnormal erythrocyte nuclear maturation and leading to ultimate effect of loss of adequate stores of the Vitamin B12. Arthralgia induced after / following cobalamin administration is rarely. Despite of that various drugs are known to cause musculoskeletal adverse events such as arthralgia, myalgia and serum sickness. We present a Case of a 54 Year Old Male, with chief complaint of fever, pallor skin, shortness of breath and tiredness. On the fifth day, patient develops cyanocobalamin induced arthralgia and main treatment of the drug induced arthralgia is the discontinuation of the responsible drug. However patients can be managed with one active form of Vitamin B12 which is methyl cobalamin that has excellent beneficial therapeutic management for Joint Pain. In this case report a rare adverse event of Vitamin B12 Injection inducing arthralgia is reported.
KEYWORDS
REFERENCES
As publishedShowing references and in-text citations exactly as published.
Cite this article
SELECT FORMAT
Jr, K. C., Deshpande, S., & Deo, S. (2020). Parenteral Cyanocobalamin Induced Arthralgia: A Case Report. Journal of Young Pharmacists, 12(4), 383-385. https://doi.org/10.5530/jyp.2020.12.97
Copyright and licence
© 2020 Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0