Journal of Young Pharmacists logo
Submit
Journal of Young PharmacistsACADEMIC PUBLISHING
Article

Phenytoin-Induced Erythroderma

1, 2, 3, 1, 1, 2★★ Corresponding author

  1. 1Department of Pharmacy Practice, TVM College of Pharmacy, Kappagal Road, Y. Nagesh Shastry Nagar, Ballari, Karnataka, INDIA.
  2. 2Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Paneer, Nitte (Deemed to be University), Deralakatte, Mangaluru, Karnataka, INDIA.
  3. 3KLE College of Pharmacy, A Constituent Unit of KAHER, Nehrunagar, BELAGAVI, Karnataka, INDIA.

CORRESPONDENCE

Sharad Chand

Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Paneer, Nitte (Deemed to be University), Deralakatte, Mangaluru, Karnataka, INDIA.

sureechand193@gmail.com

Received: 17-04-2019; Revised: 13-05-2019; Accepted: 06-06-2019.

Volume 11, Issue 3 · pp. 320-321 · 2019 · DOI: 10.5530/jyp.2019.11.65

ABSTRACT

Phenytoin is a frequently prescribed anticonvulsant/antiseizure drug due to its high efficacy. Erythroderma is an intense and widespread reddening of the skin due to inflammation which may often be associated with peeling of skin termed as exfoliative dermatitis. Erythroderma is a rare but severe Adverse Drug Reaction (ADR) of phenytoin. Here, we report a case of a patient who developed erythrodema during the treatment regimen including phenytoin prescribed for the treatment of alcoholic withdrawal seizures. ADR was confirmed by using the World Health Organization (WHO) and Naranjo’s causality assessment scale. The erythroderma condition was managed clinically by withdrawing the causal medication and administration of anti-histamines and corticosteroids with other supportive therapy. This case explains the adverse drug reaction occurring drugs used for cure. Hence there is a strong need for a pharmacovigilance programme and its awareness all over the nation.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Voora, L., Shastry, C., Bhandari, R., Sukeerthi, D., Rawal, K. B., & Chand, S. (2019). Phenytoin-Induced Erythroderma. Journal of Young Pharmacists, 11(3), 320-321. https://doi.org/10.5530/jyp.2019.11.65

    Copyright and licence

    © 2019 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0