A Case Report on Cilostazol Induced Loss of Diabetic Control
1★, 1, 1★ Corresponding author
- 1Department of Pharmacy Practice, Al Shifa College of Pharmacy, Perinthalmanna, Kerala, INDIA.
CORRESPONDENCE
Dilip Chandrasekhar
Department of Pharmacy Practice, Al Shifa College of Pharmacy, Perinthalmanna, Kerala, INDIA.
Received: 01-06-2018; Revised: 03-07-2018; Accepted: 27-07-2018.
Volume 10, Issue 4 · pp. 489-490 · 2018 · DOI: 10.5530/jyp.2018.10.107
ABSTRACT
A 69-year-old male with known case of diabetes mellitus and hypertension was admitted with wet gangrene of right greater toe. He received cilostazol 100mg twice a day for 3 days. During this period, there was a marked elevation of blood sugar requiring higher dosage of insulin. Upon withholding the suspected drug there was a marked fall in blood glucose levels indicating a positive dechallenge. Cilostazol might have loss of diabetic control by favouring intestinal glucose absorption through increased cAMP levels and GLUT2 expression necessitating management with higher dosage of insulin.
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Chandrasekhar, D., Kanjhiraparambil, N. M., & Chalappurath, D. R. (2018). A Case Report on Cilostazol Induced Loss of Diabetic Control. Journal of Young Pharmacists, 10(4), 489-490. https://doi.org/10.5530/jyp.2018.10.107
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