Journal of Young Pharmacists logo
Submit
Journal of Young PharmacistsACADEMIC PUBLISHING
Article

The Isolation of Myristicin from Nutmeg Oil by Sequences Distillation

1,2, 2, 1, 1★★ Corresponding author

  1. 1Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, INDONESIA.
  2. 2Department of Herbal Medicine, Faculty of Medicine Universitas Kristen Krida Wacana, Jakarta, INDONESIA.
  3. 3Department of Pharmacognosy -Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, INDONESIA.

CORRESPONDENCE

Effionora Anwar

Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, INDONESIA.

effionora@farmasi.ui.ac.id

Received: 31-07-2017; Revised: 21-09-2017; Accepted: 04-11-2017.

Volume 10, Issue 1 · pp. 20-23 · 2018 · DOI: 10.5530/jyp.2018.10.6

ABSTRACT

Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content.Objectives: This study aimed to increase the myristicin content of nutmeg oil by sequences distillations.Methods: Three different conditions of distillations were applied sequentially. The first, second and third distillation were at 1100C (0.2 bars), 1050C (1 bar), and 1450C (0.2 bars) respectively. Myristicin contents determined by gas chromatography-mass spectrometry (GC-MS).Results: the myristicin content of the original nutmeg oil, the first, the second, and the third distillation were 12.93%, 17.50%, 54.21%, and 83.45% respectively. The total yield of the final product resulted after the third distillation was 5.84% v/v from the original oil.Conclusion: The use of sequences distillation with a different condition can increase the myristicin content from the original nutmeg oil.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Sudradjat, S. E., Timotius, K. H., Mun’im, A., & Anwar, E. (2018). The Isolation of Myristicin from Nutmeg Oil by Sequences Distillation. Journal of Young Pharmacists, 10(1), 20-23. https://doi.org/10.5530/jyp.2018.10.6

    Copyright and licence

    © 2018 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0