Introduction: Some plants that have good efficacy for treatment is green tea, red ginger and centella. Stimulantia effectiveness the combination of extract was test with natatory exhaustion and continued by the formulation in lozenges. Methods: Have done stimulatia effectiveness test a lozenges containing the active ingridient of green tea, red ginger and centella use a mice with natatory exhaustion method. Results: The lozenges has a good effectiveness of increasing the stamina with the average result of the test 17 minutes 1 second. Conclusion: Based on the activity assay, the use of lozenges that shows result equivalent to the positive control (caffein) is use 3 times a day.
Key words: Stimulantia, Lozenges, Green tea, Red ginger, Centella asiatica.