Pharmacognostical and Phytochemical Evaluation Leaves Extract of Garcinia daedalanthera Pierre

    Published on:March 2017
    Journal of Young Pharmacists, 2017; 9(1s):S60-S64
    Original Article | doi:10.5530/jyp.2017.1s.16
    Authors:

    Sarah Zielda Najib1, Meiliza Ekayanti1, Lia Ardiana1, Rani Sauriasari1, Berna Elya2

    1Faculty of Pharmacy, University of Indonesia, Depok, 16424, INDONESIA.

    2Laboratory of Phytochemistry and Pharmacognosy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16264, INDONESIA.

    Abstract:

    Background: Garcinia daedalanthera is an Indonesian plant where commonly found in Sulawesi, Indonesia and spread out in the forest. Garcinia daedalanthera is one of Clusiaceae family that have been scientifically proven to provideantidiabetic and antioxidant activity but never been examined in pharmacognosy parameters. Pharmacognostical parameters of the leaves were studied with the aim of drawing the pharmacopoeial standards for this species. Methods: The present study was aimed to analysis the pharmacognosy of Garcinia daedalanthera including leaf morphology, microscopic characteristics, physicochemical parameters, phytochemical study, contaminant analysis and FTIR spectrum analysis. Results: The phytochemical analysis revealed the presence of flavonoids, saponins, tannin, steroids and phenols.The moisture content was 2.35%, total ash 2.51%, acid insoluble ash 0.05%, total flavonoid and phenolic content were found to be 3.121% and 14.36% (w/w). The level of Arsenic (As), Cadmium (Cd) and lead (Pb) were found under the limit (0.357 ppm) and the extract of leaves Garcinia daedalanthera Pierre does not contain bacterial contamination. Conclusion: The data generated from this study would help in standardization for pharmacopoeial and prevent adulteration of leaves extract of Garcinia daedalanthera Pierre and the authentic plant material can be explored for its pharmacological.

    Key words: Standardization, Garcinia daedalanthera extract, FTIR, Macromicroscopy study, preliminary screening, pharmacognosy study

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