Assessment of the Photoprotective Activity of Lippia Species from Brazil and Their Use as Single UV Filters in Sunscreens

    Published on:27th May 2015
    Journal of Young pharmacists, 2015; 7(4):368-372
    Original Article | doi:10.5530/jyp.2015.4.11
    Authors:

    Karla Mara Gonçalves1, Hudson Caetano Polonini1, Lyderson Facio Viccini2, Marcos Antônio Fernandes Brandão1 and Nádia Rezende Barbosa Raposo1*

    1NUPICS-Núcleo de Pesquisa e Inovação em Ciências da Saúde, Federal University of Juiz de Fora (UFJF), Minas Gerais, Brazil.

    2Instituto de Ciências Biológicas, Departamento de Biologia, Laboratório de Genética, Federal University of Juiz de Fora (UFJF), Minas Gerais, Brazil.

    Abstract:

    Objective: The present in vitro study aimed to evaluate the photoprotective activity of four plant species from Brazil. Material and Methods: Plants (Lippia brasiliensis, L. pseudothea, L. rotundifolia and L. rubella) were collected in Minas Gerais state, Brazil, and ethanolic extracts were obtained. These were incorporated in neutral lotions and their SPF, UVAPF, UVA/ UVB Ratio and Critical Wavelength were determined by diffuse transmittance spectroscopy. Results: The best results were obtained with L. brasiliensis. It was demonstrated that this species generated an estimated in vitro SPF of 9 ± 1.0, and an effective UVAPF of 8 ± 0.7, at 15% in a neutral lotion. Conclusion: Broad spectrum sunscreens were obtained when all of four species were used as single UV filter in the sunscreens formulations, although L. brasiliensis presented the best UVA/UVB balance.

    Key words: Diffuse transmittance, Lippia, Natural products, Plant extracts, Sunscreens.

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