Objective: An adverse drug reaction is a causal relationship between a drug and an event. Alcohol consumption remains a huge threat to the global health. A seizure is an event accompanied with loss of motor activity and alterations in the patients EEG. Phenytoin is one of the most commonly employed anti-seizure medication. Psychosis is defined as a condition that is associated with lots of psychological capacity associated delirium and hallucinations. Methods: Few literatures have reported psychosis associated with antiepileptic uses. Manifestations of chronic phenytoin use may induce phenytoin toxicity and psychosis. Case Description: Here we report a case of a 45 year old male patient with probable phenytoin induced psychosis while being treated for seizures in the in-patient ward. Conclusion: The long term use of phenytoin may manifest psychotic symptoms in certain population. There is a definite need of more evidence in this field and proper diagnostic and management approaches
Key words: Adverse drug reaction, Alcohol, Phenytoin, Probable, Psychosis, Seizures.